A full body drape is required to meet the CDC Guideline for Central Line and PICC Line Insertions and exchanges specified in the definition of maximum sterile precautions. This full coverage prevents microorganisms, lint and debris from getting into the patients body, hair, clothing, oral or respiratory system, pillows, blankets, sheets, or attached devices and monitoring leads. Substituting two or more small drapes does not provide the same level of protection. They shift and rub against each other aerosolizing lint and bacteria, and they do not normally cover the same area. DO NOT reposition drape after set (see AORN sterile drapes above).